Berberine (BBR), is an isoquinoline alkaloid isolated from traditional medicinal herbs and has exhibited significant antiviral efficacy against various viruses including influenza virus, HIV, human cytomegalovirus, and herpes simplex virus (HSV). It has been shown that Berberine can inhibit viral infection by directly affecting individual steps of the virus replication cycle, inhibiting viral protein translocation, or by regulating host signal pathways. Is there a possibility that it could also inhibit the COVID-19? There is no scientific evidence at this point that it will, but I am betting that it will. I take 500 mg of Berberine 3 times daily.