Vitamin D Insufficiency Linked to Diabetic Peripheral Neuropathy
In a study involving an analysis of data from a nationally representative sample of adults with diagnosed diabetes mellitus (40 years of age or older), out of which 81% were found to have vitamin D insufficiency (less than 30 ng/ml), vitamin D insufficiency was found to be associated with self-reported symptoms of peripheral neuropathy (painful sensation, tingling, numbness, loss of feeling in hands or feet). Vitamin D insufficiency was more common among Hispanics (92%) and non-Hispanic black people (98%), as compared to non-Hispanic white people (76%). In the 3 months prior to completing questionnaires, 50% of subjects reported paresthesias in their hands or feet, 37% reported pain or tinging in their hands or feet, and 38% reported numbness or loss of feeling in their hands or feet. Vitamin D insufficiency was found to be associated with the adjusted composite paresthesia measure (OR=2.12) and the adjusted numbness measure (OR=2.04). These results suggest that vitamin D ins ufficiency may be linked to peripheral neuropathy in diabetics.
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