Sesame Seed Supplementation May Reduce Oxidative Stress
The effects of sesame seeds on reducing serum lipids and enhancing antioxidant capacity were researched in this study. Hyperlipidemic patients (n=38) were divided into two groups (treatment group received 40 g white sesame seeds daily, with 240 kcal was removed from their diet) and for all individuals, the same drug treatments were considered for 60 days. Anthropometric measurements, lipid profile and oxidative stress indicators such as glutathione peroxidase (GPX), superoxide dismutase (SOD) and thiobarbituric acid reactive substances (TBARS) were measured and assessed before and after the intervention. Results showed that the diet with sesame significantly decreased the levels of serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and TC/HDL-C ratio. Lipid peroxidation (TBARS) decreased while the activities of GPX and SOD were increased. There were no significant changes in weight and BMI. Findings suggest that sesame seed supplementation decreased serum TC, LDL-C and lipid peroxidation, and increased antioxidant status in hyperlipidemic patients.