Study Spotlight

Study Spotlight

Pycnogenol Supplementation May Improve Health in Subjects with Metabolic Syndrome


In an open, controlled study involving 64 subjects between the ages of 45 and 55 years, presenting with various risk factors associated with the metabolic syndrome (central obesity, elevated triglycerides, low HDL cholesterol, high blood pressure, and fasting blood glucose), supplementation with 150 mg/d Pycnogenol (maritime pine bark extract) for a period of 6 months was found to be associated with decreases in waist circumference (in men, from 106.2 to 98.8 cm at 3 months and 98.3 cm at 6 months; in women: from 90.9 cm to 84.6 cm at 3 months and 83.6 cm at 6 months), fasting blood glucose (from 123 mg/dL at baseline to 106.4 mg/dL at 3 months and 105.3 mg/dL at 6 months), triglycerides, blood pressure, and increases in HDL cholesterol levels, as compared to a similar such group of subjects (n=66) who served as controls. Furthermore, subjects supplemented with Pycnogenol were found to have a decrease in plasma free radicals (-34.6%), which was more significant than that found in the control group. The authors conclude, "this study indicates a role for Pycnogenol" for improving health risk factors in subjects with metabolic syndrome.

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