Study Spotlight

Study Spotlight

Omega-3 Fatty Acids Supplementation and Sickle Cell Anemia


In a randomized, placebo-controlled study involving 128 patients, supplementation with omega-3 fatty acids (containing 277. 8 mg DHA and 39.0 mg EPA per capsule) was found to be associated with a reduction in the rate of clinical vasculo-occlusive events (0 compared with 1.0 per year), severe anemia (3.2% compared with 16.4%), blood transfusion (4.5% compared with 16.4%), white blood cell count (14.4% compared with 15.6%) and the OR of the inability to attend school at least once during the study period because of illness related to the disease to 0.4. The authors conclude, "The findings of this trial, which need to be verified in a large multicenter study, suggest that omega-3 fatty acids can be an effective, safe, and affordable therapy for sickle cell anemia.

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