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Nourish Your Neurons with Walnuts

Walnuts are one of nature’s most beneficial foods. They are rich sources of fatty acids, polyphenols, and nutrients that literally protect your heart and mind. In many cases, especially in studies regarding cardiovascular health, the polyunsaturated fatty acids (PUFAs) are considered the walnut’s most valuable players. But for the brain, polyphenols and other walnut nutrients may have the biggest impact.

Polyphenols in walnuts are primarily responsible for reducing the inflammation and oxidative stress in the brain. Since these conditions increase as we age, this simply food may be the perfect choice to preserve cognitive strength, memory, motor skills, and a healthy mind overall.

Even though it doesn’t seem to be “doing” anything, the central nervous system is highly energetic and demands up to a fourth of our oxygen intake. This causes oxidative reactions that can also lead to inflammation and prematurely age or damage the brain.


Human studies show that nut consumption relieves symptoms of age-related cognitive decline and depression and improves levels of brain-derived neurotrophic factor (BDNF). Levels of BDNF are involved with neural plasticity and longevity – critical for maintaining a healthy mind as we get older.

Since walnuts are readily available at most grocery stores, it makes great sense to incorporate them into your diet – your brain will thank you!


Poulose SM, Miller MG, Shukitt-Hale B. Role of walnuts in maintaining brain health with age. J Nutr. 2014 Apr;144(4 Suppl):561S-566S.

Because of the combination of population growth and population aging, increases in the incidence of chronic neurodegenerative disorders have become a societal concern, both in terms of decreased quality of life and increased financial burden. Clinical manifestation of many of these disorders takes years, with the initiation of mild cognitive symptoms leading to behavioral problems, dementia and loss of motor functions, the need for assisted living, and eventual death. Lifestyle factors greatly affect the progression of cognitive decline, with high-risk behaviors including unhealthy diet, lack of exercise, smoking, and exposure to environmental toxins leading to enhanced oxidative stress and inflammation. Although there exists an urgent need to develop effective treatments for age-related cognitive decline and neurodegenerative disease, prevention strategies have been underdeveloped. Primary prevention in many of these neurodegenerative diseases could be achieved earlier in life by consuming a healthy diet, rich in antioxidant and anti-inflammatory phytochemicals, which offers one of the most effective and least expensive ways to address the crisis. English walnuts (Juglans regia L.) are rich in numerous phytochemicals, including high amounts of polyunsaturated fatty acids, and offer potential benefits to brain health. Polyphenolic compounds found in walnuts not only reduce the oxidant and inflammatory load on brain cells but also improve interneuronal signaling, increase neurogenesis, and enhance sequestration of insoluble toxic protein aggregates. Evidence for the beneficial effects of consuming a walnut-rich diet is reviewed in this article.

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Terry is happy to provide his opinion on diet and nutrition, supplements and lifestyle choices. This information is for educational purposes only. It is not meant to replace the advice of your physician and is not to be considered medical advice, diagnosis or treatment. Should you have any concerns please contact your physician directly.
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