Low Vitamin D Status Linked to Total Adiposity, Metabolic Syndrome, and Hypertension
In a study involving 452 children (304 overweight/obese, 148 healthy, normal weight), higher 25(OH)D(3) levels were found to be significantly associated with a reduced presence of the metabolic syndrome. Furthermore, obesity, central obesity, hypertension, hypertriglyceridemia, low HDL cholesterol, insulin resistance, and the metabolic syndrome were all associated with an increased odds of having low 25(OH)D(3) levels. Comparing subjects with the lowest vitamin D3 status (<17 ng/ml) to those in the highest tertile (>27 ng/ml), the adjusted OR for hypertension was 1.72 and for the metabolic syndrome 2.30. The authors conclude, "Low 25(OH)D(3) levels in Caucasian children are inversely related to total adiposity, MetS, and hypertension."
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