Study Spotlight

Study Spotlight

Improving Vitamin D Status Benefits Women with PCOS Deficient in Vitamin D


In a retrospective, unplanned, secondary analysis of 2 cohort studies conducted during different seasons, involving 50 overweight or obese women with polycystic ovarian syndrome (PCOS), a 20-week lifestyle modification program including one cohort started in winter and finished in summer, and one started in summer and finished in winter, changes in vitamin D status were found to be inversely associated with changed in waist circumference and cholesterol levels when controlling for baseline values. Baseline 25(OH)D levels were lower in the winter cohort and increased in this cohort over the 20 weeks, whereas in the summer cohort, baseline levels were higher and levels decreased over the 20 week period. The authors conclude, "Obesity and CVD risk profiles improved in vitamin D-deficient women with PCOS after a 20-week lifestyle intervention during which vitamin D status improved with seasonal change.

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