In this double-blind, randomized, placebo-controlled, intervention study involving 103 postmenopausal women, supplementation with green tea catechins (EGCG as polyphenon E) for a period of 2 months was found to significantly reduce LDL cholesterol concentrations and glucose-related markers. Subjects were randomized to one of three groups for a period of 2 months: 1) placebo; 2) 400 mg EGCG as PPE; 3) 800 mg EGCG at PPE. The most significant change found was a decrease in LDL cholesterol in both PPE groups, as compared to placebo. Furthermore, decreases in glucose and insulin levels were found in the PPE groups (though not significant), while those levels increased in the placebo group. The authors conclude, "In summary, green tea (400- and 800-mg EGCG as PPE; ~5-10 cups) supplementation for 2 months had suggestive beneficial effects on LDL-cholesterol concentrations and glucose-related markers."
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