Can Vitamin K Deficiency be a Risk for COVID-19 Fatality? : Terry Talks Nutrition

Study Spotlight

Study Spotlight

Can Vitamin K Deficiency be a Risk for COVID-19 Fatality?


Vitamin K comes in two forms, vitamin K1 (phylloquinone) and vitamin K2 (menaquinone), but both have very different roles and abilities.

Among the many roles of Vitamin K2, it helps guide calcium into the bones and keeps it from accumulating in the arteries. However, it also may be a key to stopping the severity and the mortality of COVID-19.

That’s because vitamin K2 also prevents calcification in the fibers of other soft tissues, including the lungs. The more flexible your lungs are, the better they can withstand damage from respiratory viruses, including COVID-19.

The researchers involved with this study found that individuals with vitamin K2 deficiencies also faced worse symptoms and outcomes than those with an adequate level of the nutrient. This was also due, in part, to the fact that vitamin K keeps the cardiovascular system working smoothly, so the effect of vitamin K for preventing severity and death is not limited to its effects on the lungs, but is part of its holistic function in the body.

Other research is currently examining the role that common nutrients, including vitamin C, vitamin D, selenium, and zinc can have on the outcome of dangerous illnesses. It may be that these essential nutrients, including vitamin K2 could make a critical difference in weathering a disease or being overtaken by it.

Study Information:

Berenjian A, Sarabadani Z. How menaquinone-7 deficiency influences mortality and morbidity among COVID-19 patients. Biocatal Agric Biotechnol. 2020;29:101792. doi:10.1016/j.bcab.2020.101792

We hypothesise that manifestations of COVID-19 and comorbidities associated with the severe form of this disease could be linked to MK-7 deficiency. Therefore, this work aims to discuss how MK-7 can support the prevention and treatment of the disease during the COVID-19 pandemic.

Elastin plays a key role in providing resilience, elasticity, and deformability to dynamic tissues, namely the lungs and arteries, which has a high affinity for calcium. Vascular calcification typically initiates in the elastin fibres of the medial arterial wall. MGP is MK-7-dependent and is well-known as a calcification inhibitor in soft tissues, such as the arterial walls. Moreover, MGP plays a key role in protecting extracellular matrix proteins from possible enzymatic degradation. Elastic fibres are essential components of the extracellular matrix in the lungs, where MGP is strongly expressed.

Here is the link to the complete study: How menaquinone-7 deficiency influences mortality and morbidity among COVID-19 patients

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