Every week there is a new area of solicitation for cancer research. However, we never hear of what we Americans can do to prevent cancer. There is enough evidence today to develop effective, preventive strategies through lifestyle modifications. For most people, it may be just too hard to make changes and they will gamble on whether or not cancer may strike them. Consumption of large quantities of vegetable oils containing omega-6 fatty acids increase significantly many kinds of cancer. Tobacco is a known carcinogen and responsible for up to 20% of all cancers. 30% of all cancers are directly or indirectly related to our diet by consuming too much of what we should not eat and too little of what we should eat to prevent cancer. Most experts in the field of cancer research agree that we do not eat enough plant food, vegetables, fruits, nuts, seeds and berries which contain cancer preventing antioxidants. Alcohol, by virtue of its oral consumption, not only reaches the gastrointestinal tract but also reaches every cell in the body and is a major risk factor for the development as well as progression of various forms of cancer. Chronic alcohol consumption results in nutritional deficiencies and specifically decreases absorption of folate, vitamins B1, B2 and B12, allowing the cells to become vulnerable to the increase and free radical damage resulting in oxidative stress. Excessive calories, high consumption of processed foods, and a high calorie diet are risk factors for many kinds of cancer. As of May 2013, 66% of adults are overweight and 33% are obese. In 2008 there were 500 million people that were in the obese category worldwide. Inactivity and lack of exercise also are a major risk factor for cancer. With an educational process to discuss methods of prevention, we might reduce the incidence of cancer far better than looking for a cancer cure, but since cancer is big business, too much money is to be had by research. There is also the lack of desire by individuals to make the necessary changes to lower the risk of cancer. There will be no cure for cancer through drug therapy but only through prevention.