Ravindranathan P, Pasham D, Goel A. Oligomeric proanthocyanidins (OPCs) from grape seed extract suppress the activity of ABC transporters in overcoming chemoresistance in colorectal cancer cells. Carcinogenesis. 29 Dec 2018.
Conventional chemotherapy doesn’t always fi nish off cancer cells.
That’s why cancer can recur and spread throughout the body. When cancer cells become resistant, higher dosages of chemotherapy may not be an option. Chemotherapy drugs can make people sick, weak, and damage healthy cells in the body in the process.
But OPCs can help. They slow the growth of chemoresistant cells and inhibit proteins that otherwise help cancer cells thrive. When OPCs from French grape seed extract were combined with chemotherapy in treatment of resistant colon cancer (animal model), the result was a 70% REDUCTION IN TUMOR WEIGHT.
Ultimately, this means that OPCs from a tannin-free French grape seed extract (VX1) could make chemotherapy drugs more effective at lower dosages.
Ravindranathan P, Pasham D, Balaji U, Cardenas J, Gu J, Toden S, Goel A. Mechanistic insights into anticancer properties of oligomeric proanthocyanidins from grape seeds in colorectal cancer. Carcinogenesis. 2018 May 28;39(6):767-777.
Our bodies can only use what we absorb. If a compound from a natural medicine like grape seed extract can’t be absorbed, it can’t do any good. In an animal model of cancer, a study comparing tannin-free OPCs (VX1) against a plain, “unfractionated” grape seed extract shows the dramatic difference. IN JUST 13 DAYS…
OPCs from French grape seed extract (VX1) have greater efficacy in treating cancer than plain grape seed extract.
Toden S, Ravindranathan P, Gu J, Cardenas J, Yuchang M, Goel A. Oligomeric proanthocyanidins (OPCs) target cancer stem-like cells and suppress tumor organoid formation in colorectal cancer. Sci Rep. 2018;8(1):3335.
A specific pathway in the body, called “Hippo-YAP”, needs to be down-regulated in order to stop cancer cells from regenerating. It is a challenging pathway to block. Fortunately, OPCs from a tannin-free, French grape seed extract (VX1) are strong enough to do it.
A cell study showed that these OPCs reduced viable cancer stem cells by 71%. An animal model found that these OPCs suppressed tumor growth by 90% in 14 days with 300-600 mg daily of tannin-free, French grape seed extract (OPCs).
OPCs from a tannin-free, French grape seed extract are successful in the process of stopping cancer cells from regenerating.
Ravindranathan P, et al. A combination of curcumin and oligomeric proanthocyanidins offer superior anti-tumorigenic properties in colorectal cancer. Sci Rep. 2018 Sep 14;8(1):13869.
Tannin-free OPCs travel through many paths in the body to stop tumors. While they are powerful on their own, they work extremely well with clinically studied curcumin.
In a scientific study, French grape seed extract (VX1) and curcumin (BCM-95) blended with turmeric essential oil to enhance absorption and provide anti-inflammatory ar-turmerone—teamed up.They did incredible work together.
When OPCs are combined with curcumin, the anti-cancer effects are even stronger!
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