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Omega-3 Fatty Acids Beneficial in Treating Juvenile

Juvenile idiopathic arthritis (JIA) patients respond positively to omega-3 fatty acid supplementation. Twenty seven JIA patients (12.78 +/- 3.26 y), disease duration approximately 5.93 y (+/- 3.06 y), age of onset 6.78 y (+/- 3.26 y), were given twice daily supplements of omega-3 fatty acids over a period of 12 weeks. The study measured the effect of supplements on clinical manifestations, laboratory investigations, disease activity, functional capacity, response criteria, interleukin-1 (IL-1) and tumor necrosis factor-a (TNF-a) levels. The overwhelming majority of patients experienced improvement in the American College of Rheumatology response criteria, with significant boost in active joint count, number of swollen joints, JADAS-27, CHAQ, TNF-a, and IL-1 levels. Patients were able to decrease use of nonsteroidal anti-inflammatory drugs (NSAIDS). These results support the adjunctive use of omega-3 fatty acids in concert with conventional therapies in the treatment of pat ients with juvenile idiopathic arthritis.

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